Positron Emission Tomography (PET)

What is PET? 

Positron Emission Tomography (PET) is a diagnostic imaging technique that visualises the body’s metabolic and biochemical activity. Unlike traditional imaging methods that primarily focus on structural details, PET scans reveal functional processes at the cellular level. By detecting changes in how tissues and organs operate, PET provides detailed insights into patients’ medical condition. 

A key advantage of PET is its ability to detect subtle changes in metabolism, often before structural changes become visible. This makes it an invaluable tool in diagnosing complex conditions such as neurological disorders, cancers, and cardiovascular diseases. In many cases, PET is combined with other imaging modalities, such as Computed Tomography (CT) or Magnetic Resonance Imaging (MRI), to enhance the accuracy of diagnoses by providing both functional and structural information in a single scan. 

PET imaging is not only a diagnostic tool but also plays a crucial role in treatment planning and monitoring. It helps physicians assess the effectiveness of therapies, adjust treatment strategies, and provide patients with personalised care according to their specific needs.

PET is a diagnostic imaging technique that helps diagnose and monitor a variety of medical conditions by analysing the body’s metabolic and biochemical activity.

When is a Brain PET scan recommended?

A brain PET scan is recommended in specific situations to evaluate brain function and detect abnormalities at the cellular level. It is particularly useful when other imaging techniques, such as CT or MRI, cannot provide sufficient information.

  • Alzheimer’s disease and dementia: detects early signs of Alzheimer’s disease and distinguishes between different types of dementia.
  • Brain tumours: evaluates tumour activity, determines malignancy, and monitors response to treatment.
  • Epilepsy: identifies regions of the brain causing seizures , which helps in treatment planning.
  • Parkinson’s disease: assesses brain activity to diagnose Parkinson’s and differentiate it from other movement disorders.
  • Stroke recovery: evaluates brain metabolism and blood flow to assess damage and recovery potential after a stroke.
  • Mental health conditions: investigates conditions like depression or schizophrenia by analysing brain metabolism.
  • Traumatic brain injury: detects subtle metabolic changes not visible on CT or MRI scans.
  • Pre-surgical planning: maps brain function to guide surgeries, especially for epilepsy or tumours.
  • Unexplained neurological symptoms: explores the underlying causes of persistent symptoms such as memory loss or confusion.
  • Monitoring treatment effectiveness: assesses the impact of therapies on brain conditions, particularly for cancer or degenerative diseases.

How does PET work? 

Positron Emission Tomography (PET) operates by using a radiotracer—a small amount of radioactive material—that is introduced into the body, typically through an injection. This radiotracer is designed to mimic naturally occurring substances, such as glucose, which cells use for energy. Once administered, the tracer travels through the bloodstream and accumulates in areas of high metabolic activity, such as rapidly dividing cancer cells or active brain regions. 

As the tracer decays, it emits positrons that collide with electrons in the body, producing gamma rays. A PET scanner detects these gamma rays and processes the data to create detailed, three-dimensional images. These images highlight the metabolic processes and reveal abnormalities in function, offering insights that traditional imaging methods cannot provide. By analysing these patterns, physicians can diagnose diseases, monitor treatments, and better understand how the body is functioning at a cellular level.

PET works by detecting gamma rays emitted from a radiotracer injected into the body, creating images that show phases of brain perfusion, function, and activity.

What are the benefits of PET? 

Positron Emission Tomography (PET) offers a range of advantages that make it an essential tool in modern diagnostic and therapeutic practices, particularly for understanding complex conditions at their earliest stages.

  • Comprehensive functional imaging: reveals metabolic activity and biochemical processes, providing insights that go beyond anatomical imaging.
  • Personalised treatment planning: helps develop therapies by identifying disease extent and assessing response to treatment, particularly in cancer and neurological disorders.
  • Non-Invasive and safe: involves minimal discomfort and uses tracers with low radiation exposure, which makes it suitable for repeated use in monitoring.
  • Enhanced outcomes through hybrid imaging: when combined with CT or MRI, PET provides both functional and structural details, which helps ensure more informed clinical decisions.
  • Real-time monitoring of treatment effectiveness: tracks changes in metabolic activity during or after treatment to evaluate its success or need for adjustment.

What results can I expect? 

When you book a PET scan at Siow Neurology, our team ensures a comfortable experience from start to finish. During your initial appointment, we will discuss your medical history and explain the procedure to help you feel at ease. On the day of the scan, our skilled specialists will guide you through every step, from administering the radiotracer to completing the imaging process. 

After the scan, your results will be carefully analysed by our experienced radiologists and neurologists. Within a few days, we will provide a comprehensive report that includes detailed images and an interpretation of your scan. This report will be shared with your referring doctor or discussed directly with you during a follow-up consultation, where we will answer any questions and outline the next steps in your care plan. At Siow Neurology, our goal is to ensure you leave with clear answers and a personalised strategy for your health journey.

How many PET sessions are generally needed? 

The number of PET sessions required depends on the medical condition being evaluated and the purpose of the scan. For most diagnostic purposes, a single PET session is sufficient to provide detailed insights. However, if you are undergoing treatment for conditions like cancer or monitoring the progression of a neurological disorder, additional PET scans may be scheduled to assess treatment effectiveness or track changes over time. 

At Siow Neurology, we personalise the scanning schedule based on your medical condition, which helps ensure you receive the most accurate and timely information to guide your care. Schedule your PET scan with us today, and let our expert team provide you with clear, detailed insights to guide your next steps toward better health.

Frequently Asked Questions (FAQs) 

Preparation for a PET scan typically involves fasting for several hours before the procedure. It’s important to inform your healthcare provider about any medications you are taking and to avoid strenuous physical activity prior to the scan. Specific instructions may vary, so please follow the guidelines provided by your medical team.
During the procedure, a small amount of radioactive tracer is injected into your bloodstream. You will then rest quietly for about 30 to 60 minutes to allow the tracer to distribute throughout your body. After this period, you will lie on a table that slides into the PET scanner, where images are taken over approximately 20 to 40 minutes. It’s important to remain still during the scan to ensure clear images.
PET scans are generally safe, with the amount of radiation exposure comparable to that of other diagnostic imaging procedures. Some individuals may experience minor discomfort at the injection site. It’s crucial to inform your healthcare provider if you are pregnant, breastfeeding, or have any allergies to ensure appropriate precautions are taken.
The time frame for receiving PET scan results can vary depending on the facility and the urgency of the situation. Typically, a radiologist will analyse the images and send a report to your referring physician within a few days. Your doctor will then discuss the findings with you and outline any necessary next steps.
Insurance coverage for PET scans varies based on your provider and specific policy. It’s advisable to contact your insurance company beforehand to confirm whether the procedure is covered and to understand any out-of-pocket expenses you may incur.
Yes, you can typically resume your normal activities immediately after a PET scan. The radioactive tracer used in the procedure is generally eliminated from your body within a few hours. Drinking plenty of fluids can help expedite this process.
While CT and MRI scans provide detailed images of the body’s structures, PET scans offer information about the body’s metabolic and biochemical activity. This functional insight can detect abnormalities at a cellular level, often before structural changes become apparent. In some cases, PET scans are combined with CT or MRI to provide a more comprehensive view.
Yes, individuals with diabetes can undergo PET scans. However, special preparation may be required to manage blood sugar levels before the procedure. It’s important to inform your healthcare provider about your condition so they can provide specific instructions according to your health condition.
The frequency of PET scans depends on your medical condition and the purpose of the imaging. Your healthcare provider will determine the appropriate interval between scans based on your individual health needs and the information required for your treatment plan.

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    MT ALVERNIA HOSPITAL

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    MT ELIZABETH NOVENA SPECIALIST CENTRE

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