Gepants A new treatment for migraine

Recently there has been a lot to get optimistic about in terms of treatments for migraine. After years of using repurposed medicines, or medicines developed for other conditions, there are now specific preventive treatments developed for migraine. Four injectable calcitonin gene-related peptide (CGRP) monoclonal antibodies have been developed and approved for use on the NHS in the UK.

The gepants come as tablets and can be compared to the triptans in their role as an acute treatment, to treat a migraine attack. They should be taken at the start of an attack, as early as possible, to treat pain and associated migraine symptoms (e.g. nausea, light/noise/smell sensitivity). Some gepants can also be used as a preventive treatment for migraine, if prescribed for this use, with an oral tablet being taken every other day, to help reduce the severity and frequency of attacks.